BDBM50026863 CHEMBL268493::Nicotinamidase Inhibitor, 16::PncA Inhibitor, 2::Pyridine-3-carbaldehyde

SMILES O=Cc1cccnc1

InChI Key InChIKey=QJZUKDFHGGYHMC-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50026863   

TargetIsochorismatase family protein(Streptococcus pneumoniae)
Cornell University

LigandPNGBDBM50026863(CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA...)
Affinity DataKi:  11nMAssay Description:Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsochorismatase domain-containing protein(Caenorhabditis elegans)
Cornell University

LigandPNGBDBM50026863(CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA...)
Affinity DataKi:  22nMAssay Description:Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyrazinamidase/nicotinamidase, PncA protein(Borrelia burgdorferi)
Cornell University

LigandPNGBDBM50026863(CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA...)
Affinity DataKi:  110nMAssay Description:Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsochorismatase domain-containing protein(Caenorhabditis elegans)
Cornell University

LigandPNGBDBM50026863(CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA...)
Affinity DataKi:  110nMAssay Description:Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyrazinamidase/nicotinamidase PncA(Mycobacterium tuberculosis)
Albert Einstein College of Medicine

LigandPNGBDBM50026863(CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA...)
Affinity DataKi:  300nMAssay Description:Enzyme activity measurement by a coupled assay. initial velocities for the reaction of MtPncA were determined by monitoring the loss of absorbance a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamidase(Saccharomyces cerevisiae)
Cornell University

LigandPNGBDBM50026863(CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA...)
Affinity DataKi:  1.40E+3nMAssay Description:Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Oryctolagus cuniculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50026863(CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA...)
Affinity DataIC50:  6.00E+5nMAssay Description:Inhibition of Oryctolagus cuniculus (rabbit) AOX in liver cytosolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of California

Curated by ChEMBL
LigandPNGBDBM50026863(CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Agaricus bisporus (mushroom) tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed