BDBM50053188 1-(2-{[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylmethyl]-methyl-amino}-ethyl)-imidazolidin-2-one::CHEMBL122018

SMILES CN(CCN1CCNC1=O)Cc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12

InChI Key InChIKey=FGAZQFHCZPVRQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50053188   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50053188(1-(2-{[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylm...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to serotonin 5-hydroxytryptamine 2A receptors using a radioligand [3H]-ketanserin binding assay in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50053188(1-(2-{[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylm...)
Affinity DataIC50:  23nMAssay Description:Binding affinity to the alpha-1 adrenergic receptor using a radioligand [3H]-prazosin binding assay in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50053188(1-(2-{[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylm...)
Affinity DataIC50:  22nMAssay Description:Binding affinity to dopamine receptor D2 using a [3H]-spiperone binding assay in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed