BDBM50067028 (1E,4E)-1,5-Bis-(4-hydroxy-3-methoxy-phenyl)-penta-1,4-dien-3-one::(1E,4E)-1,5-bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one::1,5-Bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one::1,5-Bis-(4-hydroxy-3-methoxy-phenyl)-penta-1,4-dien-3-one::1,5-bis-(4-hydroxy-3-methoxyphenyl)-penta-1,4-dien-3-one::CHEMBL128729::Go-Y022
SMILES COc1cc(\C=C\C(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
InChI Key InChIKey=ISIMGBQRFXXNON-FCXRPNKRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50067028
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
University Jena
Curated by ChEMBL
University Jena
Curated by ChEMBL
Affinity DataEC50: 900nMAssay Description:Activation of Nrf2 transcriptional activity in human LNCaP cells after 6 hrs by luciferase reporter gene assay relative to tert-butylhydroquinoneMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Jena
Curated by ChEMBL
University Jena
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of 5-LO in human neutrophils using arachidonic acid as substrate preincubated for 15 mins measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Jena
Curated by ChEMBL
University Jena
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of STAT3 transcriptional activity in human HaCaT cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Jena
Curated by ChEMBL
University Jena
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli Bl21 (DE3) using arachidonic acid as substrate preincubated for 10 mins measured a...More data for this Ligand-Target Pair