BDBM50067877 6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimidine-2,4-diamine::CHEMBL337746

SMILES COc1ccccc1S(=O)(=O)c1ccc2nc(N)nc(N)c2n1

InChI Key InChIKey=AXHQKFFYWOTQEK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50067877   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067877(6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimid...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067877(6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimid...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Pneumocystis cariniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067877(6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimid...)
Affinity DataIC50:  210nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067877(6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimid...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067877(6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimid...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067877(6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimid...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed