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Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50067877'
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067877(6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimid...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067877(6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimid...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067877(6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimid...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067877(6-(2-Methoxy-benzenesulfonyl)-pyrido[3,2-d]pyrimid...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Pneumocystis cariniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed