BDBM50076047 (1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicyclo[3.2.1]oct-2-ene-2-carboxylate::3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester::CHEMBL169429

SMILES COC(=O)C1=C(CC2CCC1O2)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=PFFMWFZKIJIGTL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50076047   

TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Macaca mulatta)
Organix

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [3H]citalopram from SERT in rhesus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]WIN 35428 from DAT in rhesus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of [3H]citalopram binding to human serotonin transporter (hSERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]WIN-35428 binding to human dopamine transporter (hDAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50:  12.8nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed