BDBM50092783 CHEMBL3586404
SMILES CO[C@H]1CC[C@@H](CC1)N1C(=O)CNc2ncc(nc12)-c1ccc(nc1)C(C)(C)O
InChI Key InChIKey=UFKLYTOEMRFKAD-SHTZXODSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50092783
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of cFMS (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 651nMAssay Description:Inhibition of Flt4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair