BDBM50100174 3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylamino)-pentanoyl]-hydrazinocarbonyl}-butyric acid::3-Biphenyl-4-yl-5-{N'-[5-(4-methyl-pyridin-2-ylamino)-pentanoyl]-hydrazino}-5-oxo-pentanoic acid::CHEMBL417066

SMILES Cc1ccnc(NCCCCC(=O)NNC(=O)CC(CC(O)=O)c2ccc(cc2)-c2ccccc2)c1

InChI Key InChIKey=PACDIVMUVSJXND-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50100174   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  53nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  970nMAssay Description:Inhibition of integrin alpha-v/beta-3 mediated M21 cell adhesion to vitronectin with monoclonal antibody P1F6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of integrin alpha-v/beta-5 mediated UCLAP-3 cell adhesion on vitronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  4nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed