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Found 3 Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50100174'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  4nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-4-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50:  970nMAssay Description:Inhibition of integrin alpha-v/beta-3 mediated M21 cell adhesion to vitronectin with monoclonal antibody P1F6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed