BDBM50104372 4-[2-(4-Chloro-phenyl)-5-(4-phenoxy-phenyl)-3H-imidazol-4-yl]-pyridine::CHEMBL315613

SMILES Clc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(Oc2ccccc2)cc1)-c1ccncc1

InChI Key InChIKey=BEUJQOCLEVYLAY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104372   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104372(4-[2-(4-Chloro-phenyl)-5-(4-phenoxy-phenyl)-3H-imi...)
Affinity DataIC50:  110nMAssay Description:Affinity for human glucagon receptor in presence of Mg2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104372(4-[2-(4-Chloro-phenyl)-5-(4-phenoxy-phenyl)-3H-imi...)
Affinity DataIC50:  27nMAssay Description:Binding affinity towards human glucagon receptor in absence of Mg2+ expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104372(4-[2-(4-Chloro-phenyl)-5-(4-phenoxy-phenyl)-3H-imi...)
Affinity DataIC50:  250nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104372(4-[2-(4-Chloro-phenyl)-5-(4-phenoxy-phenyl)-3H-imi...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article