BDBM50139866 CHEMBL3764191::US10577361, E28

SMILES Cn1c(SCCCN2CCOC(C2)c2ccc(cc2)C(F)(F)F)nnc1-c1ccsc1

InChI Key InChIKey=AGPVWRLINFFKSF-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139866   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Indivior

US Patent
LigandPNGBDBM50139866(CHEMBL3764191 | US10577361, E28)
Affinity DataKi:  112nMAssay Description:[3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Indivior

US Patent
LigandPNGBDBM50139866(CHEMBL3764191 | US10577361, E28)
Affinity DataKi:  8.71E+3nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were re-suspended ...More data for this Ligand-Target Pair
In DepthDetails US Patent