BDBM50143602 20-cyclopropylmethyl-(1R,12R)-7-thia-5,20-diazapentacyclo[10.5.3.01,13.02,10.04,8]icosa-2(10),3,5,8-tetraen-6-amine::CHEMBL55671

SMILES Nc1nc2cc3c(C[C@@H]4C5CCCC[C@]35CCN4CC3CC3)cc2s1

InChI Key InChIKey=OQGLRMIBYLADSW-DOSTUVGRSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50143602   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143602(20-cyclopropylmethyl-(1R,12R)-7-thia-5,20-diazapen...)
Affinity DataKi:  0.0490nMAssay Description:Inhibition of [3H]U-69593 binding to Opioid receptor kappa 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143602(20-cyclopropylmethyl-(1R,12R)-7-thia-5,20-diazapen...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143602(20-cyclopropylmethyl-(1R,12R)-7-thia-5,20-diazapen...)
Affinity DataKi:  29nMAssay Description:Inhibition of [3H]naltrindole binding to opioid receptor delta 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143602(20-cyclopropylmethyl-(1R,12R)-7-thia-5,20-diazapen...)
Affinity DataEC50:  73nMAssay Description:Agonistic activity against Opioid receptor mu 1 in Chinese hamster ovary membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143602(20-cyclopropylmethyl-(1R,12R)-7-thia-5,20-diazapen...)
Affinity DataEC50:  2.40nMAssay Description:Agonistic activity against kappa opioid receptor in Chinese hamster ovary membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed