BDBM50145714 3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-ethoxy]-phenyl}-2-methyl-2-phenoxy-propionic acid::CHEMBL312717

SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(O)=O)cc1)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=BWQAEQBADOVIBT-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50145714   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145714(3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  69nMAssay Description:Transcriptional activation of reporter assay by human Peroxisome proliferator activated receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145714(3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataIC50:  169nMAssay Description:Displacement of PPARgamma agonist from human PPAR gamma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145714(3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataIC50:  503nMAssay Description:Displacement of PPARalpha/delta agonist from human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145714(3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataIC50:  503nMAssay Description:In vitro inhibition of human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145714(3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  69nMAssay Description:Transactivation activity for human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145714(3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataIC50:  7.02E+3nMAssay Description:In vitro inhibition of mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145714(3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  2.34E+3nMAssay Description:Transactivation activity for mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145714(3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  7nMAssay Description:Transcriptional activation of reporter assay by PPAR gamma receptor in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed