BDBM50158471 CHEMBL3781694

SMILES Cc1c(F)cccc1[C@H]1COC(N)=N1

InChI Key InChIKey=IOHOUWIYOVWGHV-SECBINFHSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50158471   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50158471(CHEMBL3781694)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50158471(CHEMBL3781694)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50158471(CHEMBL3781694)
Affinity DataEC50:  35nMAssay Description:Agonist activity at rat TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50158471(CHEMBL3781694)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50158471(CHEMBL3781694)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed