BDBM50177643 (R)-[8-chloro-6-(1-piperazinyl)-1H-benzo[5,6]]cyclohepta[1,2-b]pyridine-11-yl]-1-(methylsulfonyl)piperidine::CHEMBL383114
SMILES CS(=O)(=O)N1CCC(CC1)[C@@H]1c2ccc(Cl)cc2C(=Cc2cccnc12)N1CCNCC1
InChI Key InChIKey=ZMGCFGGMTCMSDP-HSZRJFAPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50177643
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of farnesyltransferase activity in COS7 cells transfected with Ras gene in soft agar proliferationMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of farnesyltransferase activityMore data for this Ligand-Target Pair