BDBM50193829 CHEMBL425442::N-(2-(1H-indol-3-yl)ethyl)-4-((3R,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-4-oxobutanamide

SMILES O=C(CCC(=O)N1C[C@@H]2CCCN2C[C@H]1Cc1ccccc1)NCCc1c[nH]c2ccccc12

InChI Key InChIKey=PZWWUMRKSGYBFR-BJKOFHAPSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50193829   

TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193829(CHEMBL425442 | N-(2-(1H-indol-3-yl)ethyl)-4-((3R,8...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC3R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193829(CHEMBL425442 | N-(2-(1H-indol-3-yl)ethyl)-4-((3R,8...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC5R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193829(CHEMBL425442 | N-(2-(1H-indol-3-yl)ethyl)-4-((3R,8...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC4R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193829(CHEMBL425442 | N-(2-(1H-indol-3-yl)ethyl)-4-((3R,8...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193829(CHEMBL425442 | N-(2-(1H-indol-3-yl)ethyl)-4-((3R,8...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193829(CHEMBL425442 | N-(2-(1H-indol-3-yl)ethyl)-4-((3R,8...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193829(CHEMBL425442 | N-(2-(1H-indol-3-yl)ethyl)-4-((3R,8...)
Affinity DataIC50:  0.100nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193829(CHEMBL425442 | N-(2-(1H-indol-3-yl)ethyl)-4-((3R,8...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC1R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed