BDBM50207561 CHEMBL396097::Class IIa HDAC inhibitor, Compound 6::N-hydroxy-2,2-diphenylacetamide

SMILES ONC(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=OFSBBVCLWMCGNY-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50207561   

TargetHistone deacetylase 5(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC5 (620-1122) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC7 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant C-terminal FLAG-tagged HDAC1 expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50:  750nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC4 (612-1034) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of recombinant C-terminal FLAG-tagged HDAC2 expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged HDAC6 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of recombinant HDAC8 expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed