BDBM50233360 CHEMBL4062497
SMILES Cc1cc(ccc1Cl)[C@]12N(CCN1C(=O)c1ccccc21)C(=O)c1ccc(F)c(F)c1
InChI Key InChIKey=XMSLRELXMCKGCB-DEOSSOPVSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50233360
TargetMuscarinic acetylcholine receptor M5(RAT)
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Negative allosteric modulation of rat M5 receptor expressed in CHO cells assessed as inhibition of acetyl choline-induced calcium mobilization preinc...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Negative allosteric modulation of human M5 receptor expressed in CHO cells assessed as inhibition of acetyl choline-induced calcium mobilization prei...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(RAT)
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Negative allosteric modulation of rat M5 receptor expressed in CHO cells assessed as inhibition of acetyl choline-induced calcium mobilization preinc...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Negative allosteric modulation of human M5 receptor expressed in CHO cells assessed as inhibition of acetyl choline-induced calcium mobilization prei...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human muscarinic M3 receptor expressed in CHO cells co-expressing Gqi5 assessed as intracellular calcium mobilization by calci...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by by...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in CHO cells co-expressing Gqi5 assessed as intracellular calcium mobilization by calci...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human muscarinic M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as intracellular calcium mobilization by calci...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair