BDBM50268794 Ac-Nle-c[Asp-His-DPhe-cis-4-guanidinyl-Pro-Trp-Lys]-NH2::CHEMBL444493
SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2C[C@@H](CN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)N=C(N)N)C(N)=O
InChI Key InChIKey=OOCZYZNDKCLOHE-RWHXLNGPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50268794
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataEC50: 760nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair