BDBM50273208 CHEMBL4129831

SMILES COCCCCn1c(cnc1-c1ccccc1)C(=O)N(CC(C)C)[C@@H]1CNC[C@@H](C1)C(=O)N1CCOCC1

InChI Key InChIKey=NZIIDCYRLVLIBY-RPBOFIJWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273208   

TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273208(CHEMBL4129831)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273208(CHEMBL4129831)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273208(CHEMBL4129831)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed