BDBM50278411 CHEMBL4170367

SMILES Cl.[H][C@]12Cc3ccccc3[C@@]1([H])[C@@]2([H])N[C@H]1CC[C@H](N)CC1

InChI Key InChIKey=XLRHPTGCSRKMLO-DJDKPPBHSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50278411   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278411(CHEMBL4170367)
Affinity DataEC50:  3.60nMAssay Description:Inhibition of LSD1 in human MV-4-11 cells assessed as increase in CD86 mRNA expression after 10 days by SYBR Green dye-bsed RT-qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278411(CHEMBL4170367)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to human alpha V beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278411(CHEMBL4170367)
Affinity DataEC50: >20nMAssay Description:Inhibition of LSD1 in human MV-4-11 cells assessed as increase in CD86 mRNA expression after 3 days by SYBR Green dye-bsed RT-qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278411(CHEMBL4170367)
Affinity DataIC50:  6.77E+3nMAssay Description:Antagonism of Muscarinic M2 receptors as displacement of concentration response curve of carbachol on isolated guinea-pig left atriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278411(CHEMBL4170367)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected insect cells by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278411(CHEMBL4170367)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed