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Found 3 Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM50278411'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278411(CHEMBL4170367)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278411(CHEMBL4170367)
Affinity DataEC50: >20nMAssay Description:Inhibition of LSD1 in human MV-4-11 cells assessed as increase in CD86 mRNA expression after 3 days by SYBR Green dye-bsed RT-qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278411(CHEMBL4170367)
Affinity DataEC50:  3.60nMAssay Description:Inhibition of LSD1 in human MV-4-11 cells assessed as increase in CD86 mRNA expression after 10 days by SYBR Green dye-bsed RT-qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed