BDBM50306277 CHEMBL595694::benzyl 7-oxo-2,3,7,8,9,9a-hexahydro-1H-benzo[de][1,7]naphthyridine-1-carboxylate

SMILES O=C(OCc1ccccc1)N1CCc2cccc3C(=O)NCC1c23

InChI Key InChIKey=DTGYQLDLIIBHHF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306277   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50306277(CHEMBL595694 | benzyl 7-oxo-2,3,7,8,9,9a-hexahydro...)
Affinity DataEC50:  130nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as inhibition of hydrogen peroxide-induced poly(ADP-ribosyl)ationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50306277(CHEMBL595694 | benzyl 7-oxo-2,3,7,8,9,9a-hexahydro...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human PARP1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed