Found 2 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50306277' TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome
Curated by ChEMBL
Irbm-Merck Research Laboratories Rome
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human PARP1 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome
Curated by ChEMBL
Irbm-Merck Research Laboratories Rome
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as inhibition of hydrogen peroxide-induced poly(ADP-ribosyl)ationMore data for this Ligand-Target Pair
