BDBM50314365 4-hydroxy-2-((1-methyl-4-(4-(4-methylpiperazine-1-carbonyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1092485

SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)-c1ccnc2n(C)cc(\C=C3/Oc4cccc(O)c4C3=O)c12

InChI Key InChIKey=HXANWSROTQADER-JLPGSUDCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314365   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314365(4-hydroxy-2-((1-methyl-4-(4-(4-methylpiperazine-1-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50314365(4-hydroxy-2-((1-methyl-4-(4-(4-methylpiperazine-1-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed