BDBM50322727 4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden]-methyl}phenoxy)methyl]benzeneboronic Acid::CHEMBL1173671
SMILES OB(O)c1ccc(COc2ccc(\C=C3/SC(=O)N(Cc4ccc(F)cc4)C3=O)cc2)cc1
InChI Key InChIKey=BRWUZCBSWABPMR-XKZIYDEJSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50322727
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of human recombinant ATXMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human recombinant ATX using ABTS as substrate by absorbance based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair