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Found 4 Enz. Inhib. hit(s) with Target = 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 2' and Ligand = 'BDBM50322727'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322727(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322727(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322727(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human recombinant ATX using ABTS as substrate by absorbance based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322727(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50:  88nMAssay Description:Inhibition of human recombinant ATXMore data for this Ligand-Target Pair
In DepthDetails PubMed