BDBM50327360 CHEMBL4168827
SMILES CN1CCC2(CCN(CC2)c2c(C#N)c(nc3c(Cl)c(C)[nH]c23)C(F)(F)F)C1=O
InChI Key InChIKey=UDNCNBGVKQIMOL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50327360
Affinity DataKi: 530nMAssay Description:Displacement of (C[3H]3) from NaPi2a (unknown origin) expressed in HEK293 cell membranes coexpressing tetracyclin after 1 hr by scintillation countin...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human NaPi2a expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human NaPi2c expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human Pit-1 expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: >2.60E+4nMAssay Description:Inhibition of human Pit-2 expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human NaPi2b expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair