BDBM50327360 CHEMBL4168827

SMILES CN1CCC2(CCN(CC2)c2c(C#N)c(nc3c(Cl)c(C)[nH]c23)C(F)(F)F)C1=O

InChI Key InChIKey=UDNCNBGVKQIMOL-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50327360   

TargetSodium-dependent phosphate transport protein 2A(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327360(CHEMBL4168827)
Affinity DataKi:  530nMAssay Description:Displacement of (C[3H]3) from NaPi2a (unknown origin) expressed in HEK293 cell membranes coexpressing tetracyclin after 1 hr by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transport protein 2A(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327360(CHEMBL4168827)
Affinity DataIC50:  120nMAssay Description:Inhibition of human NaPi2a expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transport protein 2C(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327360(CHEMBL4168827)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human NaPi2c expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transporter 1(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327360(CHEMBL4168827)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human Pit-1 expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transporter 2(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327360(CHEMBL4168827)
Affinity DataIC50: >2.60E+4nMAssay Description:Inhibition of human Pit-2 expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transport protein 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327360(CHEMBL4168827)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human NaPi2b expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed