BDBM50327939 7-methoxytacrine::CHEMBL1256415

SMILES COc1ccc2nc3CCCCc3c(N)c2c1

InChI Key InChIKey=APQPVVOYBLOJDY-UHFFFAOYSA-N

Data  4 KI  28 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327939   

TargetAcetylcholinesterase(Homo sapiens (Human))
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataKi:  2.09E+3nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataKi:  6.34E+3nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed