BDBM50391363 CHEMBL2148074
SMILES Oc1ccc(Cl)cc1-c1c[nH]nn1
InChI Key InChIKey=NBDFMTBYKCBTSW-UHFFFAOYSA-N
Data 17 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50391363
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of full-length human IDO1 expressed in Escherichia coli Rosetta (DE3) using L-Trp substrate by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of full-length human IDO1 expressed in Escherichia coli Rosetta (DE3) using L-Trp substrate by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 7 hr...More data for this Ligand-Target Pair