BDBM50432209 BIBR-1048::BIBR-1048-BS-RS1::DABIGATRAN ETEXILATE::Pradaxa
SMILES CCCCCCOC(=O)N=C(N)c1ccc(NCc2nc3cc(ccc3n2C)C(=O)N(CCC(=O)OCC)c2ccccn2)cc1
InChI Key InChIKey=KSGXQBZTULBEEQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50432209
Affinity DataKi: 4.5nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human thrombin preincubated for 10 mins using Ac-FVR-AMC as substrate by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human thrombin preincubated for 10 mins using Ac-FVR-AMC as substrate by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 554nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair