BDBM50441716 CHEMBL2434978

SMILES OC(=O)c1ccc(Sc2ccc(CN3CCC(CC3)N3[C@@H](CN(C4CCOCC4)C3=O)c3ccccc3)cn2)cc1

InChI Key InChIKey=BZKHTWAGPLWPPO-LJAQVGFWSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50441716   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441716(CHEMBL2434978)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441716(CHEMBL2434978)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441716(CHEMBL2434978)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441716(CHEMBL2434978)
Affinity DataIC50:  3.72E+3nMAssay Description:Antagonist activity at CCR4 (unknown origin) expressed in HEK293F cell membranes assessed as inhibition of TARC-induced calcium flux preincubated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441716(CHEMBL2434978)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441716(CHEMBL2434978)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441716(CHEMBL2434978)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in human HeLa cells assessed as inhibition of interaction of CHO cells expressing HIV-1 JRFLenv and HIV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441716(CHEMBL2434978)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed