BDBM50443249 Ischemin

SMILES Cc1cc(N=Nc2cc(c(C)cc2C)S(O)(=O)=O)c(N)cc1O

InChI Key InChIKey=UUECJWRVDTUDCB-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50443249   

TargetCREB-binding protein(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50443249(Ischemin)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of p53-CBP bromodomain interaction in human U2OS cells assessed as inhibition of p21 activation incubated overnight followed by doxorubici...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50443249(Ischemin)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair