BDBM50502492 CHEMBL4446048::US11834430, Compound 8
SMILES COc1cc(ccc1OCCOc1cccc(c1)-n1ccnc1C)C#N
InChI Key InChIKey=MYLHNIBKADVMPD-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50502492
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 0.200nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair