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Found 2 Enz. Inhib. hit(s) with Target = 'Protein-S-isoprenylcysteine O-methyltransferase' and Ligand = 'BDBM50502492'
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50502492(CHEMBL4446048 | US11834430, Compound 8)
Affinity DataIC50:  0.200nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50502492(CHEMBL4446048 | US11834430, Compound 8)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed