BDBM50502759 CHEMBL4435596

SMILES Cc1cccc(c1)[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1cccnc1

InChI Key InChIKey=QANXJBIOBLNORO-TYKWCNGQSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502759   

TargetTransient receptor potential cation channel subfamily V member 6(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50502759(CHEMBL4435596)
Affinity DataIC50:  50nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTransient receptor potential cation channel subfamily V member 6(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50502759(CHEMBL4435596)
Affinity DataIC50:  320nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition by calciu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB