BDBM50528237 CHEMBL4550952

SMILES Cc1ccc(CC(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3)ccc2F)cc1C

InChI Key InChIKey=WJGXQVTUIDSRQL-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528237   

TargetReceptor-interacting serine/threonine-protein kinase 3(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528237(CHEMBL4550952)
Affinity DataKd:  72nMAssay Description:Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system after 1 hr by quantitative PC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528237(CHEMBL4550952)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system after 1 hr by quantitative PC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed