BDBM50542998 CHEMBL4638738

SMILES NS(=O)(=O)c1ccc(Oc2ccc(F)c(Cl)c2)c(CN2CCC3(C2)CCNCC3)c1

InChI Key InChIKey=DJBOQHAPBAAZEH-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542998   

TargetSon of sevenless homolog 1(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50542998(CHEMBL4638738)
Affinity DataEC50:  3.31E+3nMAssay Description:Agonist activity at His6-tagged-human SOS1 catalytic domain (564 to 1049 residues) expressed in Escherichia coli BL21-CodonPlus-RIPL cells assessed a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSon of sevenless homolog 1(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50542998(CHEMBL4638738)
Affinity DataKd:  3.12E+3nMAssay Description:Displacement of FITC-labelled probe from human SOS1 catalytic domain (564 to 1049 residues) incubated for 20 mins by fluorescence polarization compet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed