BDBM50544339 CHEMBL4639379
SMILES CN(C)CCNC(=O)[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2cc(C)ccc2[nH]1
InChI Key InChIKey=DAPGTEFWLXXRFD-UNMCSNQZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50544339
Affinity DataIC50: 4nMAssay Description:Displacement of [His[125I]]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [His[125I]]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.58nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at human MOR expressed in CHOK1 cells assessed as inhibition of DAMGO-induced increase in cAMP accumulation measured after 10 min...More data for this Ligand-Target Pair
Affinity DataEC50: <7.94E+3nMAssay Description:Agonist activity at rat KOR expressed in CHOK1 cells assessed as increase in cAMP accumulation measured after 10 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at rat KOR expressed in CHOK1 cells assessed as inhibition of U50488-induced increase in cAMP accumulation measured after 10 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Displacement of [3H]DAMGO from recombinant human MOR measured after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 251nMAssay Description:Agonist activity at human MOR expressed in CHOK1 cells assessed as increase in cAMP accumulation measured after 10 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Displacement of [3H]U69593 from KOR (unknown origin) measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair