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Found 3 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50544339'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544339(CHEMBL4639379)
Affinity DataIC50:  398nMAssay Description:Displacement of [3H]U69593 from KOR (unknown origin) measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544339(CHEMBL4639379)
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at rat KOR expressed in CHOK1 cells assessed as inhibition of U50488-induced increase in cAMP accumulation measured after 10 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544339(CHEMBL4639379)
Affinity DataEC50: <7.94E+3nMAssay Description:Agonist activity at rat KOR expressed in CHOK1 cells assessed as increase in cAMP accumulation measured after 10 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed