BDBM50548363 CHEMBL4753164

SMILES CN(C)Cc1cc(nn1C)-c1ccnc(Nc2ccn3c(C)nc(-c4nnc(C)o4)c3c2)n1

InChI Key InChIKey=PAZNLQHSWVMGIW-UHFFFAOYSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50548363   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50548363(CHEMBL4753164)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of recombinant full length SYK (unknown origin) by biochemical Omnia assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50548363(CHEMBL4753164)
Affinity DataKd:  400nMAssay Description:Binding affinity to ZAP70 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50548363(CHEMBL4753164)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human ERG by plate-based planar patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed