BDBM50570566 CHEMBL4849604

SMILES COC(=O)C(=N/Nc1ccc(OC)cc1)\C(=O)C(F)(F)C(F)(F)C(F)(F)F

InChI Key InChIKey=IHRHACRFXNFJBN-AQHIEDMUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50570566   

TargetLiver carboxylesterase(Sus scrofa)
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570566(CHEMBL4849604)
Affinity DataIC50:  103nMAssay Description:Inhibition of porcine liver carboxylesterase using 4-NPA as substrate preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570566(CHEMBL4849604)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570566(CHEMBL4849604)
Affinity DataIC50:  111nMAssay Description:Inhibition of human recombinant CES1 expressed in baculovirus infected BTI insect cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed