BDBM50571039 CHEMBL4877846

SMILES CC(C)n1nc(C)c(c1C)-c1nc2c(ccnc2[nH]1)-c1ccc2[C@@H](CCCCc2c1)NC(=O)c1nc(no1)C(C)(C)C

InChI Key InChIKey=XHKFYFCKCXKVPO-XMMPIXPASA-N

Data  11 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50571039   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  58nMAssay Description:Inhibition of BTK in human whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  3nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCytochrome P450 2C9(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Rattus norvegicus)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  11nMAssay Description:Inhibition of BTK in rat whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human FGRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  27nMAssay Description:Inhibition of human SRCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  60nMAssay Description:Inhibition of human Aurora-AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMisshapen-like kinase 1(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  91nMAssay Description:Inhibition of human MINK1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human BTKMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB