BDBM50581604 SEP-363856::SEP-856::Sep-363856::ULOTARONT::Ulotaront

SMILES CNC[C@@H]1OCCc2ccsc12

InChI Key InChIKey=ABDDQTDRAHXHOC-QMMMGPOBSA-N

Data  1 IC50  4 EC50

PDB links: 6 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50581604   

TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581604(SEP-363856 | SEP-856 | Sep-363856 | ULOTARONT | Ul...)
Affinity DataEC50:  38nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581604(SEP-363856 | SEP-856 | Sep-363856 | ULOTARONT | Ul...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human TAAR1More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50581604(SEP-363856 | SEP-856 | Sep-363856 | ULOTARONT | Ul...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at D2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50581604(SEP-363856 | SEP-856 | Sep-363856 | ULOTARONT | Ul...)
Affinity DataIC50:  2.40E+4nMAssay Description:Agonist activity at D2 (unknown origin) by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50581604(SEP-363856 | SEP-856 | Sep-363856 | ULOTARONT | Ul...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at 5HT1A (unknown origin)More data for this Ligand-Target Pair