BDBM50607512 CHEMBL5218811
SMILES COC1CN(C1)[C@@H]1COc2c(cnn2C1)S(=O)(=O)NC(=O)Nc1c2CCCc2cc2CCCc12
InChI Key InChIKey=TYGORWHFDBOYDY-INIZCTEOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50607512
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Jecure Therapeutics
Curated by ChEMBL
Jecure Therapeutics
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS and nigericin-stimulated human PBMC cells assessed as reduction in IL-1beta release preincubated w...More data for this Ligand-Target Pair