BDBM527618 US11186588, Example 103::US11186588, Example 99

SMILES COc1cncc(CNNC(=O)OC(C)(C)C)c1

InChI Key InChIKey=QBUXRDGFSWQGGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 527618   

TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Ayumi Pharmaceutical

US Patent
LigandPNGBDBM527618(US11186588, Example 103 | US11186588, Example 99)
Affinity DataIC50:  289nMAssay Description:A549/NF-κB-luc cells (available from Panomics, Cat No. LR0051) were prepared at 375,000 cells/mL in the culture medium. The 375,000 cells/mL A54...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Ayumi Pharmaceutical

US Patent
LigandPNGBDBM527618(US11186588, Example 103 | US11186588, Example 99)
Affinity DataIC50:  1.64E+3nMAssay Description:A549/NF-κB-luc cells (available from Panomics, Cat No. LR0051) were prepared at 375,000 cells/mL in the culture medium. The 375,000 cells/mL A54...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent