BDBM647790 US20240025919, Compound 17
SMILES C[C@@H]1Oc2nc(c(F)c3nc(OC[C@@]45CCCN4C[C@H](F)C5)nc(N4C[C@H]5CC[C@H](N5)[C@@H]14)c23)-c1cc(N)cc(F)c1C(F)(F)F
InChI Key InChIKey=YGXIHUNYFUZFHL-JLBGJYTOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 647790
Affinity DataIC50: 0.133nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Affinity DataIC50: 0.559nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1-mediated nucleotide exchange in KRAS WT. In this assay, the SOS1-promote...More data for this Ligand-Target Pair