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Found 1 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM647790'
TargetGTPase KRas(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647790(US20240025919, Compound 17)
Affinity DataIC50:  0.559nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1-mediated nucleotide exchange in KRAS WT. In this assay, the SOS1-promote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent