BDBM8963 CHEMBL32823::Homodimeric Tacrine Analog 3b::N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-1,2,3,4-tetrahydroacridin-9-amine::Tacrine Dimer 3b::Tacrine-Based Inhibitor 2f::tacrine homobivalent compound 3a
SMILES C(CCCNc1c2CCCCc2nc2ccccc12)CCCNc1c2CCCCc2nc2ccccc12
InChI Key InChIKey=ITZOKHKOFJOBFS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 8963
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 10.5nMAssay Description:Inhibition of equine serum BuChEMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of equine BChE incubated with compounf for 5 mins before addition of substrate S-butyrylthiocholine iodide by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human AChE incubated with compounf for 5 mins before addition of substrate acetylthiocholine iodide by Ellman's methodMore data for this Ligand-Target Pair