BDBM8963 CHEMBL32823::Homodimeric Tacrine Analog 3b::N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-1,2,3,4-tetrahydroacridin-9-amine::Tacrine Dimer 3b::Tacrine-Based Inhibitor 2f::tacrine homobivalent compound 3a
SMILES C(CCCNc1c2CCCCc2nc2ccccc12)CCCNc1c2CCCCc2nc2ccccc12
InChI Key InChIKey=ITZOKHKOFJOBFS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 8963
Affinity DataKi: 0.163nMAssay Description:Competitive inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate at pH 8 by stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of horse BuChEMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of Equine ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.66nMAssay Description:Inhibition of human serum recombinant BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 10.5nMAssay Description:Inhibition of equine serum BuChEMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine chloride as substrate preincubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of BuChE in human plasma using butyrylthiocholine iodide as substrate by Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Inhibition of mouse serum BuChEMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Inhibition of BuChE in Swiss Webster mouse whole blood serum using butyrylthiocholine iodide as substrate preincubated for 10 mins followed substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human serum BuChe using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by susbtrate addition and ...More data for this Ligand-Target Pair